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Back to Marco Island: Sun, Surf, Serious Lectures


Considering the reaction to February’s Advances in Genome Biology and Technology conference, Rick Wilson, co-director of Washington University’s Genome Sequence Center, pronounces the GSAC-alternative event a success.

“The only complaint I heard was that people wanted some afternoons off so they could hang on the beach,” he says. The meeting was sponsored by companies including MJ Research, Sequenom, Applied Biosystems, and Amersham Pharmacia Biotech.

Roughly 500 attendees got a sneak preview of Eric Green’s presentation for the genome symposium at the NIH — shots of sequencing teams and a visual tale of the sequence race flashed up as the Star Wars theme song played.

Organizers asked Green to adapt the show for the conference “instead of boring remarks from the introductory chair — notably me,” Wilson jokes. It was a hit: “Everybody wanted a copy.”

Though science was strongly emphasized throughout the conference, the private sector was well represented. “You have a lot [of] good quality science being done in the industrial sector,” Wilson says. “You wouldn’t want to exclude industry speakers.” (You would, however, ask that speakers come from the science side rather than the PR side, he says.)

The conference ended with a flourish, as the last night was slated for a disco fever party. Even the most reserved sequencers found themselves becoming dancing queens.

— Meredith Salisbury


The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.