Axel Visel Links Cell Cycle-Inhibitor Genes to Risk of Heart Disease | GenomeWeb

A polymorphism in a non-coding stretch of chromosome 9p21 has been linked to an increased risk of developing coronary artery disease, say researchers at the Department of Energy's Lawrence Berkeley National Laboratory. This region regulates a pair of cell cycle-inhibitor genes, and the vascular cells of people with the variant divide and multiply more quickly than usual, leading to narrowed coronary arteries.

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