Skip to main content
Premium Trial:

Request an Annual Quote

ALSA Renews Funding for Biomarker Project

NEW YORK, Nov. 3 (GenomeWeb News) - A consortium including researchers from Metabolon has received funding to continue research to find biomarkers that indicate the presence of amyotrophic lateral sclerosis, the ALS Association said yesterday.

 

The organization did not release actual figures for individual projects, said Mark Yard, from ALSA's research depeartment.

 

The award will last one year, beginning Nov. 1 and ending Oct. 31, said Metabolon's Stephanie Ferrell.

 

The ongoing project has already produced a candidate panel of molecules in body fluids that differ between people with the disease and controls. Researchers identified a set of 19 proteins.

 

Researchers will continue testing samples with a focus on cerebrospinal fluid, since the highest level of biomarkers may occur there, and seek proteins and metabolic biomarkers that are specific to ALS. 

 

Metabolon previously received funding from ALSA in February 2004 to find biomarkers that indicate the presence of ALS, also called Lou Gehrig's disease. Metabolon has also received grants from NIH's National Institute of Environmental Health Sciences and from National Institute of Neurological Disorders and Stroke since the beginning of 2004.

 

The consortium includes researchers from Massachusetts General Hospital, Metabolon, Duke University, and University of Pittsburgh.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.