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Agilent Offering $600M in Debt to Pay for Acquisitions, Other Needs

NEW YORK (GenomeWeb News) — Agilent Technologies said today it is offering $600 million in senior notes and plans to use the net proceeds for general corporate purposes, including repurchases of outstanding shares of common stock, acquisitions, working capital, and capital expenditures.
 
The offering, expected to close Oct. 29, will be handled through book-runners Citi Markets & Banking and J.P. Morgan Securities.
 
Agilent said the notes will mature in November 2017 and will bear interest at 6.5 percent per year.

The Scan

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.

Study Explores Animated Digital Message Approach to Communicate Genetic Test Results to Family Members

In the Journal of Genetic Counseling, the approach showed promise in participants presented with a hypothetical scenario related to a familial hereditary breast and ovarian cancer syndrome diagnosis.

Computational Tool Predicts Mammalian Messenger RNA Degradation Rates

A tool called Saluki, trained with mouse and human messenger RNA data, appears to improve mRNA half-life predictions by taking RNA and genetic features into account, a Genome Biology paper reports.

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.