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Affymetrix to Repurchase Notes

NEW YORK (GenomeWeb News) – Affymetrix disclosed in a filing with the US Securities and Exchange Commission that it has entered into an agreement to repurchase $69.1 million of its 3.5 percent senior convertible notes due 2038.

The firm said that it entered into the agreement yesterday to repurchase the notes in private transactions. It expects to pay a total consideration of $50.6 million in cash and close the repurchase on June 2.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.