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ABI, Vanderbilt Collaborate to Study Novel Tissue-Imaging Technology

NEW YORK, Feb. 12 - Applied Biosystems and Vanderbilt University on Tuesday said they plan to co-develop a procedure for proteomics and small-molecule analysis using a novel direct molecular-imaging technique developed at the school.

The collaboration is intended to combine ABI's mass spec experience with a tissue-imaging tool developed by Richard M. Caprioli, who directs the mass spec and proteomics research center at Vanderbilt and who will lead the school's efforts in the partnership. Caprioli's technique is hoped to help ABI "analyze the distribution, identification and characterization of biomolecules and drugs in specific tissues, cells and organs," according to a joint statement.

Financial terms of the agreement were not disclosed.

Caprioli's procedure marries MALDI mass spec with visual tissue and cellular imaging to pinpoint the location of culprit cells, the partners said. The technique can also help track the location of drugs and their metabolites in the treatment of various disorders, including cancer, thay added. 

"We believe that this collaboration may lead to new and more productive proteomics workflows to better integrate protein analysis with other established and relevant methodologies in biomedical research for understanding complex biological phenomena," said Stephen A. Martin, director of ABI's proteomics research center.

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