Allergy News on in vitro diagnostics for allergy testing. Multi-Ancestry GWAS Leads to Loci Linked to Hundreds of Human Phenotypes Using genotyping data for hundreds of thousands of individuals from Japan and beyond, researchers found more than 5,000 new associations, as well as disease classification clues. New Leukocyte-Linked Loci Uncovered With Multi-Ancestry Genomes Using genome sequence data for more than 61,800 diverse TOPMed participants, researchers found seven new loci with significant ties to leukocyte traits. Penicillin Allergy Linked to HLA-B Allele in Genome-Wide Association Study The analysis drew on thousands of cases and controls and suggested a role for an autoimmune factor in penicillin allergies. Single-Cell Expression Analysis of Nasal Polyps Suggests Mechanisms of Chronic Inflammation The researchers found that the diversity of epithelial cell types was reduced in nasal polyps, which contained few glandular and ciliated cells and were enriched in basal cells. Research Groups Seek Biomarkers of Asthma Drug Resistance in Populations With African Ancestry Premium CU Denver and UC San Francisco teams are independently performing whole-genome sequencing to find genes involved in reduced efficacy of a common bronchodilator drug. Dec 5, 2017 Acute Peanut Allergy Contributors Suggested by Blood Transcriptomic Study Oct 20, 2017 Food Allergy GWAS Leads to Five Susceptibility Loci Nov 22, 2016 Euroimmun, Angsana Form Allergy Diagnosis, Testing Partnership Nov 8, 2016 Rutgers NJMS, Cepheid Describe 10-Color Assay for Extensively Drug-Resistant TB Premium Sep 8, 2016 NIH Launches $20M Competition for New Antimicrobial Resistance Diagnostics Breaking News CDC Awards $22M to Combat Antimicrobial Resistance, Infectious Diseases Pan-Cancer Analysis Reveals Unique Features in Tumors From Younger People Breast Cancer Therapy Response Predicted by Multiomic Machine Learning Model Cytena Inks China Distribution Deal for Single-Cell Isolators Freenome Raises $300M in Series D Financing More Than Dozen Genetic Loci Linked to Amyotrophic Lateral Sclerosis Risk The Scan Less Than Half An effort to reproduce key findings from high-profile preclinical cancer studies finds less than half could be replicated, according to the Scientist. Still Some SARS-CoV-2 Sequencing Holes The Wall Street Journal reports that viral genomic surveillance has improved in the US, though says there are still gaps. Avoiding Passing Them On People with known disease-linked genetic variants are turning to in vitro fertilization so as to not pass those variants to their children, the Washington Post says. PNAS Papers on Long Cell-Free DNA in Maternal Plasma, Genetic Propensity for Voting In PNAS this week: long, cell-free DNA of maternal and fetal origins identified in maternal plasma, and more.