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Advances in Spatial Genomics

Researchers from the Broad Institute and MIT have used RNA editing and single-cell RNA sequencing to record when RNA molecules were transcribed.

The first stage generated a range of tools and resources for studying the nucleus in time and space including publicly available datasets and software.

The new plate-based protocol developed at the Karolinska Institute combines low-coverage WGS and SMART-Seq2 transcriptomics for single-cells.

10x will develop a third genomics platform, possibly combining Cartana's more sensitive chemistry with ReadCoor's instrument.

The transcriptomic study of human iPSC-derived dopaminergic neurons elucidated how gene expression changed in response to cytotoxic and genetic stressors.