Advances in Clinical Genomics Profiling
Pediatric Genetic Diagnoses Cost-Effective With First-Tier WGS, Economic Study Suggests
In pediatric cases from Italy, researchers found that first-tier genome sequencing can be a cost-effective diagnostic strategy within the willingness-to-pay thresholds considered.
After Prenatal Screening Study Picks up Cancer Risk Variants, Researchers Want Clearer Guidelines
Premium
Researchers seek more guidance on handling cancer risk variants detected in prenatal screening after nearly 5 percent of specimens in a study had such variants.
UK Study Supports Use of Whole-Genome Sequencing in Standard Cancer Care
The researchers found that whole-genome sequencing yielded more comprehensive information than relying on cancer panels.
Preeclampsia Linked to MicroRNA Markers in Maternal Blood
Researchers uncovered extracellular microRNA biomarkers in maternal blood samples that tracked with early stages and severity of the pregnancy complication.
Cervical Cancer Multiomic Study Uncovers Informative Intratumor Heterogeneity States
With single-cell, spatial, and experimental approaches, researchers defined eight "meta-programs" linked to the tumor immune microenvironment and clinical features.