Uduak Grace Thomas
The consortium will gather Nigerians' genomic, phenotypic, and clinical data in six geopolitical regions to study non-communicable and infectious diseases.
In addition to developing standards for proteomics, metabolomics, and other kinds of data, DNAnexus will develop tools to help reviewers quickly and easily assess analysis pipelines.
The company uses systems biology approaches and AI methods to model and analyze causal pathways in diseases including neurological cancers and Alzheimers.
The standards address ongoing data analysis issues including ways of securely sharing and analyzing genomic information across platforms and mechanisms for consistently identifying sequences.
Project partners will expand on infrastructure developed by DNAstack for accessing genomic data and explore patient consent models that support nationwide sharing.
Data from MMRF's Immune Atlas will be included in its recently launched CureCloud, a registry of clinical, genomic, and EHR data from multiple myeloma patients.
Metascape uses data from over 40 knowledgebases and 10 model organisms to provide functional enrichment, interactome analysis, gene annotation, and membership search capabilities.
DARTS uses deep learning-based techniques to leverage public RNA-sequencing datasets to make predictions about alternative splicing in individuals datasets.
The company shared details of its methods and results of some internal experiments but has been met with skepticism by members of the research community.
MSK's PathoMAN achieved 94 percent and 81 percent concordance with results from three commercial labs for pathogenic and benign variants, respectively.