Purigen Biosystems, a Bay Area biotech company founded in 2012, recently received $150,000 in Phase I Small Business Innovation Research funding from the National Institutes of Health to develop a device for nucleic acid sample prep.
Using a microfluidic device called SlipChip, a cell phone camera, and cloud computing, a California Institute of Technology team has shown the superiority of digital over real-time isothermal PCR under perturbed experimental conditions.
In Cambodia's Ratanakiri Province, main roads project like spokes from the small city of Banlung, population 17,000. Here, next to the local health department, a team of Cambodian and Belgian researchers intent on eliminating malaria parked a mobile PCR lab last fall.
Molecular diagnostics company DxTerity Diagnostics was recently awarded a $280,000 Small Business Innovation Research contract from the National Cancer Institute to develop a test for susceptibility to radiation sickness during cancer treatment.
Ramping up concentrations of polymerase and dNTPs, and lengthening reaction time in PCR on formalin-fixed paraffin-embedded samples overcomes common barriers to detection, according to recently published research.