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John Gilmore

Staff Reporter
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Articles Authored by John Gilmore

Apr 13, 2021

FDA-Led Group Evaluates Performance of RUO Liquid Biopsy Assays to Inform Practice Guidelines

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The researchers found that the reliable sampling of rare circulating tumor DNA fragments served as the key challenge for developing liquid biopsy assays.

Apr 08, 2021

Armed With $55M in New Funding, Nucleix to Further Invest in Early-Stage Lung Cancer Dx

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The Rehovot, Israel-based firm expects to soon receive marketing clearance from the US Food and Drug Administration for its methylation-based Bladder EpiCheck test.

Mar 31, 2021

Startup MiCareo Targets Rare Cell Isolation Market With Flow Displacement Instrument

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The Taiwan-based startup aims to publish data showing the instrument's prognostic value in colorectal cancer, as well as launch a new version, by this summer.

Mar 25, 2021

Startup Tethis Targets Early-Stage Breast Cancer Detection With CTC Sample Prep Platform

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The Italian firm believes its liquid biopsy method can help assays detect early-stage breast cancer to minimize mammography screening prior to curative surgery. 

Mar 19, 2021

NephroSant Readies Launch of Kidney Transplant Rejection Assay

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Following the launch of its urine-based Qsant assay later this year, the firm plans to develop updated versions of it with new biomarkers for different disease indications.  

Mar 17, 2021

Metabolic Marker Helps Identify Lung Cancer-Linked Circulating Tumor Cells

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The method, which uses a metabolic marker called hexokinase-2, could be developed to predict cancer patient prognosis and determine progression-free survival.

Mar 15, 2021

Dana Farber Team Applies PCR Method to ID Microsatellite Instability in Tumor-Derived Samples

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The group aims to adapt the method, which detects poly-adenine tails, to monitor for minimal residual disease in late-stage colon cancer patients after surgery.

Mar 11, 2021

Broad Team to Improve Minimal Residual Disease Detection With Mutation Enrichment Sequencing Method

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The team plans to integrate the method, which combines mutation enrichment with duplex sequencing, into its platform to detect minimal residual disease in blood.

Mar 04, 2021

Agilent Charges Into Liquid Biopsy Space with Resolution Biosciences Acquisition

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The firm will build liquid biopsy companion diagnostic tests that complement its tissue-based assays and are tailored for drugs developed by pharma partners.

Mar 01, 2021

TGen-Led Team Spots Pediatric, Pancreatic Cancer From cfDNA Fragments in Urine

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The liquid biopsy method analyzes fragment ends within recurrently protected regions in cell-free DNA from a patient's urine sample.  

The Scan

Pause Recommended

The FDA and CDC call for a pause in administering Johnson & Johnson's SARS-CoV-2 vaccine while reports of rare blood clots are looked into, reports the Wall Street Journal.

Science and a Side of Diplomacy

According to the Associated Press, a Swiss program aims to shepherd long-term science projects and diplomacy.

New Studies of B.1.1.7

CNN reports that two new studies suggest the B.1.1.7 SARS-CoV-2 variant may be more transmissible, but may not lead to more severe disease.

PNAS Papers on Acute Kidney Injury, Parental Expression in Horse Placenta, Sea Urchin Microbes

In PNAS this week: analysis of pathway affecting acute kidney injury, parental-specific allelic expression in horse placenta, and more.

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