By using array-synthesized guide-donor oligonucleotide pairs, the team's gene editing technique allows accurate and detectable phenotyping in yeast cells.
The blood-based test could eventually become a rapid point-of-care diagnostic in the ICU, with startup Microbiome as a commercial vehicle.
The study identified one genetic and three protein-based biomarkers associated with outcome in Pseudomonas bloodstream infections.
Using genetic probes and fluorescent scanning, the firm plans to market the $20 test for pathogens that cause urinary tract infections and biological warfare.
The firm has developed microbubbles that bind to target molecules based on surface antibodies.
The team used genetic scoring to identify infants without a family history of the disease who had more than a 10 percent risk for developing islet antibodies.
Jean-Laurent Casanova aims to identify single-gene mutations that compromise the immunity of normally healthy individuals and lead to severe infectious disease.
CU Denver and UC San Francisco teams are independently performing whole-genome sequencing to find genes involved in reduced efficacy of a common bronchodilator drug.
Lancet, developed by the New York Genome Center, uses colored de Bruijn graphs to jointly analyze tumor and normal reads.
By using menstrual effluent samples, the decidualization assay detects genetic biomarkers that may be linked to endometriosis.
US News & World Report writes that genetic testing of lung tumors can help identify treatments for patients.
A team of researchers plans to sample Loch Ness for environmental DNA, according to Newsweek.
The New York Times writes about the appearance of mosaicism in healthy people.
In PNAS this week: insecticide resistance patterns Anopheles gambiae mosquito, transcriptome patterns in Pseudomonas aeruginosa during infection, and more.