Catherine Shaffer

Articles Authored by Catherine Shaffer
The 53-gene biomarker signature showed promise in predicting immunotherapy response in high-risk triple-negative and HR-positive breast cancer.
A score developed using UK Biobank data can identify patients at high and low risk for blood cancer progression and is starting to be used at Dana-Farber Cancer Institute.
Behavioral Nudges in Study Increase Germline Genetic Testing Referrals but Not Patient Uptake
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At AACR, a study explored the impact of a chain of default notifications in prompting physician referrals and patient adoption of genetic testing in colorectal cancer patients.
Polygenic Risk Score Shows Potential in Personalizing Chemotherapy for Pediatric AML Patients
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At ASH's annual meeting, researchers reported that patients with low scores on a 10-SNP test fared better when they got clofarabine plus the standard 7+3 course of chemo.

Aussie Variant Classification Effort Aims to Reduce Uncertainty in Hereditary Blood Cancer Diagnosis
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The researchers hope to determine whether tens of thousands of variants in RUNX1 and GATA2 increase predisposition to blood cancers.
Genomic Test IDs Pancreatic Cysts Likely to Progress to Cancer Better Than Standard Guidelines
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UPitt is hoping the latest data demonstrating the utility of its 22-gene PancreaSeq test will help drive adoption and reimbursement.

Through an early-access program, the company is hoping to show that its platform can identify measurable residual disease in AML more accurately than current methods.
High tumor-specific mRNA levels were associated with increased risk of disease progression in 6,590 patient tumors across 15 cancer types.