Caroline Hopkins Legaspi

Patients whose lymphomas were considered high-risk according to ctDNA analyses were less likely to benefit from the widely used chemotherapy regimen.

Across three studies, researchers demonstrated how various biomarkers can inform trial design and predict lymphoma patients' outcomes on CAR T-cell therapy.

A Cambridge University study found phrases touting the benefits of genomics research without acknowledging limitations can turn off the very people researchers need to engage most.

The recent JCO Precision Oncology study could bolster the research use case for Veracyte's Decipher GRID database in better defining prostate cancer subgroups.

Culmination Bio's 4.5 million biospecimens and longitudinal omics and clinical data may help Cofactor rapidly advance the OncoPrism assay into multiple cancer types.

An analysis of whole-exome sequencing results presented at AACR suggests many people with hereditary cancer risk variants don't fall under current NCCN guidelines.

The firm unveiled early validation data for its CRISPR-based functional genomics platform, which it hopes to commercialize as another tool doctors can use to individualize cancer care. 

Somatic 9p24.1 copy number alterations predicted the degree to which HPV-negative advanced squamous head and neck cancers benefitted from Keytruda and Opdivo.

Studies at ESMO showed the importance of repeat biomarker testing to guide treatment after resistance to AstraZeneca's Tagrisso, but tissue-based testing remains a hindrance. 

In new guidelines, an expert panel recommended IHC and PCR for certain cancer types and pointed out knowledge gaps supporting NGS in other settings.