Andrea Anderson
Andrea Anderson covers genomics research studies and translational research for GenomeWeb. Find her on Twitter at @andyandy_tk.

Articles Authored by Andrea Anderson
Investigational Cancer Drug Deemed Highly Mutagenic in Cell Line Sequencing Study
Using whole-genome sequencing on drug-exposed cell lines, researchers saw high mutation rates in control cell lines intermittently treated with a compound called CX-5461.
Comparison of 239 Primate Genomes Reveals Conserved Regulatory Sequences
By aligning and comparing whole-genome sequences for 239 species, researchers identified regulatory elements that have become constrained specifically in primates.
Cannabis Use Disorders Linked to Population-Specific Risk Loci in GWAS Meta-Analysis
Researchers flagged cannabis use disorder-associated loci in African, East Asian, European, and admixed American populations before digging into related traits and behaviors.

Liquid Biopsy-Based Colorectal Cancer Screening Lacks Cost-Effectiveness, Economic Analysis Finds
A simulation study suggests colonoscopy remains the most cost-effective CRC screening method, as liquid biopsy carries a far higher price per life-year gained.
Taiwan Biobank GWAS Analyses Lead to Hundreds of New Quantitative Trait Loci
Researchers searched for genetic contributors to 36 quantitative traits in Taiwan Biobank participants, comparing results to biobank data from Japan and the UK.
Teams Track Embryo-Wide Development With Single-Cell Transcriptomic Strategies
Researchers used single-cell RNA sequencing and other methods for the large-scale phenotyping of wild type and genetically altered mouse and zebrafish embryos.
Late-Onset Alzheimer's Disease Features Thwarted by Protective Variant
A homozygous version of the Christchurch variant appeared to reduce disease-related features in mouse models and cells containing a late-onset Alzheimer's-linked APOE4 mutation.
Airway Microbiome Signatures Found for Respiratory Conditions
Researchers linked hospital-acquired pneumonia to altered representation of core airway microbes, while flagging pathogens in acute respiratory distress syndrome signatures.

Rheumatoid Arthritis Inflammatory Subtypes, Treatment Responses Uncovered in Synovial Tissue Study
With the help of single-cell RNA sequencing, single-cell CITE-seq, and other approaches, researchers saw six synovium-based inflammatory subtypes marked by distinct cell states.
Icelandic Study Links Actionable Genetic Variants to Reduced Lifespan
Using sequence data for almost 58,000 Icelanders, Decode Genetics researchers showed that actionable genotypes were associated with earlier death.