Adam covers proteomics and life science mass spectrometry for GenomeWeb.
However, a shift within the field towards experiments comprising larger numbers of samples and conditions may give DIA an advantage in the future.
In a recent study, researchers combined genomic and proteomic data to identify mutations responsible for a pair of rare monogenic neutrophil diseases.
The study made use of a high-resolution mass spec approach developed by University of Minnesota scientists that allows for untargeted discovery of DNA adducts.
The approach allows researchers to profile the protein complexes present in a sample in much the same way they have the individual peptides and proteins.
The researchers presented new reagents and software for de novo peptide sequencing, an emerging technology with potential in proteomics and biopharma.
In initial testing, the approach distinguished between stage I cancer cases and healthy controls with 95 percent sensitivity and 100 percent specificity.
The resource provides a look at protein localization patterns across the proteome as well as responses to events like alternative splicing and drug perturbation.
The firm is using collaborations to access the large, diverse cohorts it needs to support its goal of commercializing its SomaScan system as a clinical platform.
The team compiled these proteins in three panels that could help researchers better assess plasma sample quality in protein biomarker work.
The company is currently using the model, named EDGE, in its own personalized cancer vaccine work and in collaboration with outside immunotherapy developers.
The former commissioner of the FDA has returned to the venture capital firm New Enterprise Associates as a special partner on the healthcare investment team.
Astronauts have edited yeast genes on the International Space Station in an experiment designed to show how cells repair themselves in space.
Emory University has found that two of its researchers failed to divulge they had received funds from China, according to the Atlanta Journal-Constitution.
In Science this week: influence of the nuclear genome on human mitochondrial DNA, and more.