The researchers identified 669 and quantified 332 proteins in single cells, making this one of the most comprehensive mass spec-based experiments of its kind.
The reagents are intended for use in a recently developed workflow designed to address the precursor interference issue that has troubled the labeling method.
University of Oxford researchers used DNA scaffolds to build custom peptide nanopores that they said could make nanopore-based protein analysis more feasible.
According to a company official, the findings indicate the role of polyfunctional T cells in CAR T efficacy and the usefulness of single-cell protein analysis.
With the release of its Q Exactive UHMR system and a new $130 million NIH program, the company sees opportunity to expand use of its cryo-EM and mass spec techs.
Major releases were relatively sparse at ASMS as many vendors focused instead on the development of applications and workflows for their existing platforms.
The study combined large-scale protein post-translational modification datasets with protein-protein interaction data to profile cell signaling in lung cancer.
The approach combines in vitro screening using phage and yeast display with screening of antibodies in tumor-bearing mice to assess their activity in vivo.
Working independently, two research teams have combined CRISPR-based targeting and APEX labeling to identify proteins linked to specific portions of the genome.
Lawmakers have asked four direct-to-consumer genetic testing companies to explain their privacy policies and security measures, according to Stat News.
