Adam covers proteomics and life science mass spectrometry for GenomeWeb.
Researchers' picks range from emerging tools like deep learning to fundamental issues like false discovery rates and infrastructure for mass spec data sharing.
Highlights included mass spec-focused developments like data-independent acquisition and ion mobility along with platforms including Thermo Fisher's Q Exactive.
A survey asking researchers for their thoughts on the key developments in the field turned up applications ranging from clinical to structural.
Data privacy has been an issue in genomics for some time, but new regulations and improved technology could force proteomics to confront it, as well.
With new instruments and workflows able to quantify thousands of proteins in as little as five minutes, 2019 was the year proteomics cracked its throughput problem.
Researchers from France's DreamPore and their collaborators used a nanopore to distinguish between 15 of the 20 proteinogenic amino acids.
According to its developers, the software allows for the quantification several hundred proteins in five-minute DIA analyses of undepleted plasma.
The database of proteins secreted into blood provides a resource for basic research as well as a potential list of targets for drug and diagnostics development.
The firm, a spin-out of Barts Cancer Institute, is developing a mass spec-based test for identifying AML patients likely to respond to the drug midostaurin.
The researchers suggested that the system's combination of speed and high coverage could enable new applications within the imaging mass spec space.
The Washington Post reports that a Russian Academy of Sciences commission has led to the retraction of hundreds of scientific papers.
The Los Angeles Times' Daily Pilot reports the chief executive of Vantari Genetics has pleaded guilty in a kickback scheme.
News 4 Jax reports that a Florida bill to prevent life and long-term care insurers from using genetic information in their coverage decisions has easily passed one committee.
In Science this week: potentially pathogenic mutations found in hematopoietic stem cells from young healthy donors, and more.