With Pacific Biosciences sequencing, researchers found DNA N6-methyladenine modifications in the human genome and noted a role for it in tumorigenesis.

The researchers developed a protocol for dengue and chikungunya virus detection, which they plan to continue to test for outbreak monitoring and diagnostics.

The syndromes — HLRCC and SDH PGL/PCC — suppress DNA repair by homologous recombination, rendering tumors vulnerable to PARP inhibitors. 

Silicon Valley VC firm DFJ led the investment in Verge, which is applying machine learning to the development of new drugs for Parkinson's and ALS.

The plaintiffs claim that Qiagen's QIAseq kits infringe Archer's US Patent No. 10,017,810, which covers parts of its Anchored Multiplex PCR (AMP) technology.

Researchers characterized genetic, transcriptomic, and clinical features in advanced prostate cancers that emerged from treatment.

The Associated Press reports that the US government wasted $341,000 on travel by former Health and Human Services Secretary Tom Price.

Women who post YouTube science videos get more critical comments and more comments about their appearance than male video hosts, the New York Times reports.

The Wall Street Journal writes that participating in genetic research brings up the specter of past research ethics lapses for some African Americans.

In PLOS this week: sequences influencing yeast prion aggregation or degradation, dengue virus genetic variants affect transmission dynamics, and more.

Blood is a proven, reliable sample source when it comes to DNA analysis; however, it is time consuming, expensive and an invasive collection for donors. Finding a comparable source of genetic material that is more cost effective and less invasive would be extremely beneficial. Could saliva be the answer?  Read this white paper for an in-depth analysis of DNA quality, sample type functionality/ease-of-use and costs associated with saliva and blood for DNA collection.

For any analysis of the gut microbiota, it is essential to capture an accurate microbiome snapshot of the richness and relative abundance of microbes present at the moment of collection. Each of collection and transportation methods has the potential to expose samples to conditions incompatible with microbiome stabilization. Failure to properly stabilize the microbiome during sample collection, transport and processing risk obscuring the biological and clinical meaning of the microbiome profile. 

RNA sequencing is rapidly gaining popularity in research and drug development with distinct advantages over microarrays and other technologies. Considerations for sample preparation, sequencing strategy and bioinformatics are critical for consistent quality data, especially when dealing with challenging FFPE
samples.


Learn how BGI used its extensive NGS experience to optimize complete workflows and QA processes to
obtain the best results.