The grants include funding for five new clinical sites, a new metabolomics core, and increased model organism capabilities.

Using SNP profiles, gut microbe metagenomics, and other data, researchers identified host and microbe factors influencing circulating levels of CVD markers.

The financing round will support uBiome's ongoing efforts to commercialize its clinical microbiome analysis, sexually-transmitted disease, and gut wellness tests.

Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.

➢ Human induced pluripotent stem cell (iPSC) technology has provided unique ways to understand and
potentially treat human diseases using cells from individual patients.
➢ iPS cells are amenable to genomic modifications using site-specific gene editing technologies such as
CRISPR/Cas9, by which we can correct/ introduce precise disease causing mutations in patient or healthy
iPSCs, respectively.
➢ Genome edited iPSCs and their isogenic control (or parental line) offer highly-controlled experimental models
for reliable comparison of results.

The goal of this experiment was to utilize the Echo 525 Liquid Handler in assembling five, five-piece assemblies by substituting modular DNA pieces at the nanoliter scale. The Labcyte Echo Liquid Handler enables lower-cost methods and workflows to produce high-quality synthetic DNA constructs.

Introduction to In Vivo Probe Validation:

Before beginning a large animal study, it is critical to confirm that your labeled targeting agent is specific to the intended target within the biological complexity of the whole animal. Understanding the biodistribution and clearance of a labeled targeting agent is critical for meaningful image analysis and interpretation. This guide will provide an overview of how to validate a targeting agent in vivo.