Genetics, Genomics & Molecular Diagnostics News

UC can still salvage its CRISPR IP rights after last week's decision, but a long-shot appeal in federal court is the only possibility for total victory.

A genome-wide association study involving more than 52,000 men led to variants linked to male pattern baldness, along with early SNP-based attempts to predict the trait.

The Thermo Fisher subsidiary is not liable to Promega in the US for selling infringing forensic DNA kits in Europe, containing US-manufactured Taq polymerase.

The RNA-based blood test takes less than five hours to detect the presence or absence of infection in patients who may have sepsis.

NanoString said its sequencing technology harnesses its expertise in optical barcodes and that it would develop it for clinical use to complement its existing products.

The company sells the portable Hunter Real-Time PCR instrument for DNA analysis and a portfolio of test kits for use in food safety, food fraud, and microbiologically influenced corrosion.

The company sells the portable Hunter Real-Time PCR instrument for DNA analysis and a portfolio of test kits for use in food safety, food fraud, and microbiologically influenced corrosion.

The company sells the portable Hunter Real-Time PCR instrument for DNA analysis and a portfolio of test kits for use in food safety, food fraud, and microbiologically influenced corrosion.

A Karmagenes researcher has lost his position after reportedly admitting to data fabrication, according to Retraction Watch.

Two neuroscientists write in Nature News that solving the "reproducibility crisis" in science may require changing the requirements for publication.

In Nature this week: genomic analysis of prehistoric New Mexicans, a nanopore method for mapping DNA methylation, and more.

A new study finds that adding missing good bacteria to the skin microbiome of atopic dermatitis patients decreases Staphylococcus aureus colonization.

Genotoxicity workflows performed manually are subject to workflow bottlenecks, where the throughput is inherently limited, and active time spent performing the tests reduces the lab’s overall efficiency. Additionally, variability associated with operator technique and laboratory conditions could lead to a loss in precision, or worse, systematic errors that can skew results. This article demonstrates automated imaging as it pertains to the comet and gamma-H2AX assays in order to simplify genotoxicity assay workflows and provide robust results.

Stringent guidelines of quality assurance and control (QA/QC) serve as the foundation for dependable and reproducible results in any analytical endeavor. Here we highlight step-by-step, the measures implemented by Myriad RBM that take Luminex xMAP technology to a high level of reproducibility and ruggedness. The Myriad RBM platform combines the sensitivity and dynamic range of microsphere-based immuno-multiplexing with the precision and dependability of automated liquid handling.

Serpins (serine protease inhibitors) regulate key intracellular and extracellular pathways, but conformational variants of this complex family of protease inhibitors are often underrepresented in proteomic analyses. This white paper from Biotech Support Group describes bead-based separation products within the NuGel family of proteomic enrichment products that enable investigations of serum serpins. Functional profiles of serpin proteoforms can then be associated with disease phenotypes, gene mutations, and dysregulated mechanisms.