Genetics, Genomics & Molecular Diagnostics News

The test is approved as a tool to identify which patients with a kind of ovarian cancer are likely to benefit most from Tesaro's Zejula (niraparib).

At the American College of Medical Genetics and Genomics annual meeting in Phoenix, WuXi presented results from a pilot study involving 190 individuals.

At the ACMG annual conference in Phoenix last week, several labs and companies discussed their efforts in healthy genome sequencing.

For the first time, the researchers also found a clear difference in risk factors for high-grade glioblastoma versus low-grade glioma.

ACLA said the goal of the delay is to redefine "applicable laboratories" and give labs and CMS more time to collect data that will inform market-based pricing.

Developed by a team at Babraham and Karolinska institutes, the panel could improve stem cell resetting methods and research in the field more generally. 

The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.

In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.

This application reports a method to monitor the common systemic response to cancer. We spectrally quantified over 200 serum proteins, and most notably enriched for sub-populations of the protease inhibitor Alpha-1-Antitrypsin, which would not have been observable without the method. From this data, we solicit that protein markers from categorical panels can distinguish a cancer serum phenotype at very early stages, possibly even before presentation of any clinical evidence.

This paper introduces development work being undertaken at Cambridge to create a new state of the art “-omics” analysis hardware and software platform that employs the open source software framework OpenCB. Such advancements in analytics platforms are vital to translate advances in population-scale -omics into personalized medicine technologies.

This white paper shares insights and best practices to design, implement and optimize on premise public, private, and hybrid cloud architectures. Such architectures mix file and object approaches to achieve an optimal balance between cost, performance, data governance, and protection requirements.