Researchers looked at the prevalence and effects of whole-genome duplication events across cancers using targeted sequenced data for almost 10,000 advanced cases.

The syndromes — HLRCC and SDH PGL/PCC — suppress DNA repair by homologous recombination, rendering tumors vulnerable to PARP inhibitors. 

Silicon Valley VC firm DFJ led the investment in Verge, which is applying machine learning to the development of new drugs for Parkinson's and ALS.

The plaintiffs claim that Qiagen's QIAseq kits infringe Archer's US Patent No. 10,017,810, which covers parts of its Anchored Multiplex PCR (AMP) technology.

The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.

Blood is a proven, reliable sample source when it comes to DNA analysis; however, it is time consuming, expensive and an invasive collection for donors. Finding a comparable source of genetic material that is more cost effective and less invasive would be extremely beneficial. Could saliva be the answer?  Read this white paper for an in-depth analysis of DNA quality, sample type functionality/ease-of-use and costs associated with saliva and blood for DNA collection.

For any analysis of the gut microbiota, it is essential to capture an accurate microbiome snapshot of the richness and relative abundance of microbes present at the moment of collection. Each of collection and transportation methods has the potential to expose samples to conditions incompatible with microbiome stabilization. Failure to properly stabilize the microbiome during sample collection, transport and processing risk obscuring the biological and clinical meaning of the microbiome profile. 

RNA sequencing is rapidly gaining popularity in research and drug development with distinct advantages over microarrays and other technologies. Considerations for sample preparation, sequencing strategy and bioinformatics are critical for consistent quality data, especially when dealing with challenging FFPE

Learn how BGI used its extensive NGS experience to optimize complete workflows and QA processes to
obtain the best results.