Two recent studies found that as many as 20 percent of adults may have disease-associated variants, despite having no symptoms or evidence of family history.
The organization named the institutions that will be performing the proteomic and proteogenomic analyses planned to for the five-year, $65 million effort.
Using array-based miRNA profiles for individuals treated for prostate cancer, researchers identified 37 miRNA with differential expression in cases with recurrence.
The Stanford University and Fox Chase Cancer Center team found that some mutations dramatically increased cancer risk, while others had a more modest effect.
Even in schizophrenia cases lacking intellectual disability, investigators found that rare mutations in genes normally resistant to loss-of-function changes were enriched.
The approach uses the recombinase Cre along with next-generation sequencing to detect and identify protein-protein interactions in yeast two-hybrid experiments.
DuPont Pioneer has acquired the exclusive rights to ERS Genomics' portfolio of CRISPR-Cas genome-editing technologies for all plant and agricultural applications.
