A recent study examining the websites of 30 DTC genomics firms found that many do not follow international recommendations for disclosing information to customers.
A team from Radboud University in the Netherlands performed a new detailed and transparent cost analysis for sequencing based on both static costs, and factors that may differ from institution to institution.
Researchers are making mutations in a cell's genome to mark it and later read out that information to create cell lineage maps and chemical interaction histories.
Bruker said the new agreement would allow it to develop the platform for use in pathology labs, including building clinically validated content libraries.
Genetic analysis of single nucleotide polymorphisms must be accurate, reliable and economical to be a viable part of human genetic research, drug discovery, and diagnostics. This study demonstrates the ability of the IntelliQube, a fully integrated liquid handling and real-time quantitative PCR instrument, to successfully multiplex SNP assays in a single well and decrease thermal cycling times without compromising data quality.
This white paper offers advice from two industry experts, Jill Northup from Medical College of Wisconsin, and Philip Cotter from ResearchDx, on setting up a clinical NGS laboratory. The paper covers the general principles of CLIA certification and their specific application to clinical NGS, as well as considerations on implementing informatics to support validated workflows.
Next-generation sequencing (NGS) of bisulfite-converted DNA to detect methylation status with per-base resolution is currently restricted by input requirements, requiring at least 50 ng of DNA. This Application Note shows how the unique chemistry of the Accel-NGSMethyl-Seq DNA Library Kit enables the construction of high complexity libraries for:
• Genome-wide methylation analysis from 5 ng of human cell-free DNA (cfDNA).
