Privately owned Oxford Nanopore offers a range of tools and and instruments based on a proprietary nanopore-based DNA and RNA sequencing technology.

The company presented Color Data as a resource for variant classification scientists and hopes it will inspire industry peers to similarly share data.

Researchers at Memorial Sloan Kettering Cancer Center identified clinically actionable germline mutations in 8.5 percent of about 2,700 unselected lung cancer patients.

The collaboration agreement includes support for development, regulatory submission, and commercialization of tests to guide use of Novartis' drug portfolio.

The five startup companies are focused on molecular diagnostics, precision oncology, personalized medicine, and more.

The test is approved to gauge germline BRCA mutations in advanced breast cancer patients who may benefit from treatment with Pfizer's PARP inhibitor Talzenna.

The company plans to use the technology, originally developed by Good Start Genetics, to offer sample preparation solutions and data analysis for NGS.

The firm said that the assay uses vaginal or rectal swabs to identify Group B Streptococcus DNA in about an hour. It has filed for 510(k) clearance with the US FDA.

This year's Breakthrough Prize winners include a pair that developed a therapy for spinal muscular atrophy.

The New York Times reports on how white supremacists misconstrue genetic research, concerning many geneticists.

Researchers find that people's genetics influence their success at university, but that it is not the only factor.

In Nature this week: approach to identify genetic variants that affect trait variability, application of read clouds to microbiome samples, and more.

DNA quantification and normalization are required in most genomics workflows, and are usually routinely implemented after the initial nucleic acid purification step. The versatility of the classical absorbance technique still makes it the go-to method for many applications, as the concentration of all DNA and RNA types can be determined using the specific empiric extinction coefficient for each nucleic acid type.

Quantitative PCR (qPCR) is a preferred method for quantification of low amounts of DNA or cDNA due to its high sensitivity, specificity and reproducibility. Consistently high and uniform qPCR efficiencies are crucial for accurate relative quantification of gene expression levels, low copy gene detection or absolute quantification of NGS libraries1.

Oct
03
Sponsored by
Illumina

Genomics is facilitating a deeper understanding of cancer biology and through clinical research, new biomarkers are emerging that pave the way for next-generation therapeutics to help fight cancer in a more personalized way.

In this webinar, Sandip Patel, MD will provide a review of biomarker research and discoveries in the field of Immunotherapy and Garret Hampton, PhD will discuss Illumina’s vision for Oncology and share how genomics will enable broader availability of comprehensive tumor sequencing to explore complex biomarkers and assess tumor mutational burden.