The project is informing participants of familial hypercholesterolemia genetic test results, and hereditary breast and ovarian cancer, and Lynch syndrome results will follow.
With RNA sequence, expression quantitative trait locus, genome-wide association, and other data, researchers identified disease-related genes in the kidney glomerulus and tubule compartments.
The NHS will expand on existing projects such as the 100,000 Genomes Project and will offer people with rare diseases the opportunity to sequence their genomes.
The NHS will expand on existing projects such as the 100,000 Genomes Project and will offer people with rare diseases the opportunity to sequence their genomes.
New data has shown that the firm's platform could help stratify patients for treatment with antibody-drug conjugates by finding those whose CTCs express enough of the target.
New data has shown that the firm's platform could help stratify patients for treatment with antibody-drug conjugates by finding those whose CTCs express enough of the target.
California Institute of Technology's Frances Arnold was awarded half this year's Nobel Prize in Chemistry, while the University of Missouri's George Smith and the MRC Laboratory of Molecular Biology's Gregory Winter will split the other half.
Genomics is facilitating a deeper understanding of cancer biology and through clinical research, new biomarkers are emerging that pave the way for next-generation therapeutics to help fight cancer in a more personalized way.
In this webinar, Sandip Patel, MD will provide a review of biomarker research and discoveries in the field of Immunotherapy and Garret Hampton, PhD will discuss Illumina’s vision for Oncology and share how genomics will enable broader availability of comprehensive tumor sequencing to explore complex biomarkers and assess tumor mutational burden.
➢ Human induced pluripotent stem cell (iPSC) technology has provided unique ways to understand and potentially treat human diseases using cells from individual patients. ➢ iPS cells are amenable to genomic modifications using site-specific gene editing technologies such as CRISPR/Cas9, by which we can correct/ introduce precise disease causing mutations in patient or healthy iPSCs, respectively. ➢ Genome edited iPSCs and their isogenic control (or parental line) offer highly-controlled experimental models for reliable comparison of results.
The goal of this experiment was to utilize the Echo 525 Liquid Handler in assembling five, five-piece assemblies by substituting modular DNA pieces at the nanoliter scale. The Labcyte Echo Liquid Handler enables lower-cost methods and workflows to produce high-quality synthetic DNA constructs.