Researchers from the US, Sierra Leone, and the UK have garnered genetic evidence suggesting that the current Ebola virus disease outbreak in West Africa involves a form of the virus not linked to recent outbreaks in the region. They sequenced the genomes of 99 Ebola virus isolates from 78 patients treated in Sierra Leone between late May and mid-June of this year and found that the strain appears to have diverged from other Ebola virus lineages originating in Middle Africa around a decade ago.
Pacific Biosciences has received a $10 million payment from Roche for hitting a development milestone that is part of the commercialization and license agreement the companies struck in 2013. PacBio didn't disclose what development milestone had been met, but noted that it may receive up to $30 million for reaching additional development milestones. It had received an upfront payment of $35 million at the signing of the deal, under which Roche is developing molecular diagnostics on the SMRT sequencing platform.
Three US funding agencies, along with partners in the UK and Israel, will provide up to $12 million next year to support multidisciplinary research projects that will use genomics among other methods to better understand how infectious disease pathogens are transmitted and evolve. The projects will be funded under the Ecology and Evolution of Infectious Diseases program, and will aim to create quantitative or computational knowledge about and models of infectious disease transmission.
This online seminar will provide an overview of new tools for screening stem cells — in particular, the use of RNA detection probes to detect pluripotency gene expression in live embryonic and induced pluripotent stem cells by fluorescence microscopy without the need for manipulation of the cells.