Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
USPTO Rescinds Controversial Patent Rule Changes Proposed by Prior Administration
The USPTO also jointly filed a motion with GlaxoSmithKline to dismiss and vacate a federal district court decision in a lawsuit that sought to prevent the rules – which were viewed by many in the biotech industry as hindering IP protection – from taking effect.
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