SuperGen to Screen Cancer Drug Targets for GSK

October 26, 2009

By a GenomeWeb staff reporter

The agreement includes a $3 million investment for compound library screening, as well as royalties and milestones. SuperGen said total payments from GSK could potentially exceed $375 million.

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Young Investigator Profile

Martin Beck

European Molecular Biology Laborator
Group Leader, Structural and Computational Biology Unit

Macromolecular Assemblies

Martin Beck's research group at EMBL combines biochemical approaches, proteomics and cryo-electron microscopy to study the structure and function of large macromolecular assemblies. The end goals of this work include developing integrated workflows for structure determination of large macromolecular assemblies such as the nuclear pore complex, elucidation of their function through real-time imaging, and ultimately revealing the steps of their assembly and disassembly process.
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Papers of Note

Family-Based Whole-Genome Sequencing Reveals Candidates for Mendelian Disease
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Researchers at the Institute for Systems Biology and Complete Genomics have identified candidate disease-causing genes for Miller syndrome and ciliary dyskinesia, both Mendelian disorders. They sequenced the genomes of a family of four, allowing them to determine recombination sites with precision (at 99.999 percent accuracy) and identify rare single-nucleotide polymorphisms. "Our results demonstrate the unique value of complete genome sequencing in families," the authors write.

Resequencing the Domestic Chicken Genome
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SuperGen to Screen Cancer Drug Targets for GSK

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