PTB Proteins Induce RNA Looping
Lamichhane, Daubner et al., PNAS
Researchers in the US and Switzerland report that polypyrimidine tract-binding proteins induce RNA looping ― a finding they deduced using FRET, NMR spectroscopy, and in vivo splicing data. They show that two PTB RNA recognition motifs can bind two distant pyrimidine tracts, bringing their 5' and 3' ends in close proximity, thus inducing loop formation.
Stocks of Several Tool Vendors Rose Sharply in First Half of '09
July 06, 2009
Among the top stocks in the Index for the first half of the year were Compugen and Exact Sciences, which both rose nearly 400 percent. Sequenom topped decliners with a fall of 80 percent.
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