Genome-Wide Meta-Analysis for Serum Calcium Identifies Significantly Associated SNPs near the Calcium-Sensing Receptor (CASR) Gene
Kapur et al., PLoS Genetics
An international team of researchers reports its genome-wide association study of serum calcium's association with SNPs in or near the calcium-sensing receptor gene on 3q13. "This genome-wide meta-analysis shows that common CASR variants modulate serum calcium levels in the adult general population," the researchers write, adding that their "results show that CASR is a key player in genetic regulation of serum calcium in the adult general population."
Study Validates RainDance's Microdroplet PCR Technology for Targeted Resequencing
The study, published in Nature Biotechnology, found that RainDance Technologies' microdroplet-based PCR technology was more scalable than standard PCR for sequence enrichment, with comparable sensitivity and accuracy.
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