Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Stronger-than-Expected Demand for HiSeq Contributes to 50 Percent Boost in Sequencing Sales for Illumina in Q2
So far, Illumina has shipped more than 100 HiSeq instruments for revenue, representing "the fastest instrument scale-up in the company's history for the most complex product it has ever built."
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