Sequencing and Analysis of the Hydra Genome
Chapman, Kirkness et al., Nature
An international research collaboration reports their sequencing and analysis of the Hydra magnipapillata genome, and compare it to the genomes of several other organisms. "The Hydra genome has been shaped by bursts of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of gene structure and gene content that parallel simplification of the Hydra life cycle," the authors write. They team suggests that comparisons of the Hydra genome to the reported sequences of other animals have helped them to elucidate the evolution of several of the organism's characteristics.
Stanford Method Enables Researchers to Profile Gene Expression in FFPE Tumor Samples
January 26, 2010
In a proof-of-concept study published last week in PLoS One, the method, called 3'-end sequencing for expression quantification, or 3SEQ, performed much better than microarrays in profiling gene expression in FFPE tumor samples.
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