Layer, Chiang, et al. Genome Biology
Proof-of-Principle Study Shows MspA Is Superior to Alpha-Hemolysin for Protein Nanopore Sequencing
The MspA pore is smaller than nanopores made from the alpha-hemolysin protein and has a funnel-like shape that improves its ability to read single bases. The MspA pore also has a lower signal-to-noise ratio than alpha-hemolysin.
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