Norwegian Consortium Assembles, Annotates Cod Genome from 454 Data

November 03, 2009

The cod is among the first vertebrates to have its genome assembled entirely from next-generation shotgun sequencing data. In a second project phase, which may also involve short-read sequencing technologies, the researchers plan to fill in gaps in the genome, improve the annotation, and sequence the transcriptomes and genomes of additional cod samples from different geographic areas.

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In this issue of In Sequence

Young Investigator Profile

Christopher Maher

University of Michigan Medical School
Research Investigator

Gene Fusions and Transcriptome Sequencing

Christopher Maher is focused on elucidating gene fusions, which he first became acquainted with during his potdoctoral work at the Michigan Center for Translational Pathology. Maher hopes to continue discovering novel gene fusions as well as draw new findings out of already-known gene fusions. Last year, he published a paper in Nature in January of 2009 entitled "Transcriptome sequencing to detect gene fusions in cancer," which he says provides a validation for the approach of using next-gen sequencing to find gene fusions in cancer. This was followed up by a PNAS paper in July which demonstrated the gene fusion concept using paired-end transcriptome sequencing.
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Aβ as an Antimicrobial Peptide
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Joel McComb is leaving his post as senior VP and GM of Illumina's Life Sciences business to become COO at Synthetic Genomics. McComb will depart Illumina and take on the new position at SGI, where he will report to founder and CEO J. Craig Venter, effective March 1.
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Science
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Norwegian Consortium Assembles, Annotates Cod Genome from 454 Data

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