Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
International Team Sequences Genomes of Two Ant Species
By sequencing and comparing the genomes of ant species with distinct features and social structures, researchers from the US and China have started exploring the genetic and epigenetic factors contributing to ant morphology, behavior, and more.
New to GenomeWeb? Register quickly here for free access.