Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Illumina Countersues Life Technologies in Ongoing Sequencing Patent Row
Illumina and Solexa denied all of Life's and ABI's allegations of patent infringement; asserted that ABI's licensed patents are invalid; and countersued Life and ABI for allegedly infringing four Solexa patents with their SOLiD sequencing system.
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