Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
DNAnexus Aims to Alleviate Next-Gen Sequence Analysis Headache with Cloud-based Service
The Palo Alto, Calif.-based firm recently launched web-based data management and functional genomics-analysis services for users of Illumina and SOLiD sequencers. It hopes to attract customers based on both ease of use and pricing.
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