Sequencing and Analysis of the Hydra Genome
Chapman, Kirkness et al., Nature
An international research collaboration reports their sequencing and analysis of the Hydra magnipapillata genome, and compare it to the genomes of several other organisms. "The Hydra genome has been shaped by bursts of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of gene structure and gene content that parallel simplification of the Hydra life cycle," the authors write. They team suggests that comparisons of the Hydra genome to the reported sequences of other animals have helped them to elucidate the evolution of several of the organism's characteristics.
CSHL Team Finds Algorithm for Read-Depth CNV Detection Complements Paired-End Mapping Approaches
September 01, 2009
The scientists found that they were able to capture structural variants that other approaches missed. They plan to use their method, in combination with others, to analyze CNVs in large-scale human genome studies such as the 1000 Genomes Project and a planned large-scale schizophrenia genome study.
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