Correlagen Purchases Helicos Instrument to Develop New Genetic Tests

September 29, 2009

Correlagen, which has a CLIA-certified laboratory and is based in Waltham, Mass., plans to use the Helicos platform for new genetic tests that require resequencing "broad panels" of genes in the areas of cardiology, endocrinology, neuropsychiatry, and immunology.

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In this issue of In Sequence

Young Investigator Profile

Sumit Chanda

Associate Professor
Sanford-Burnham Medical Research Institute

Unraveling Complex Host-Pathogen

The Chanda lab is studying cellular proteins required for both influenza A and retrovirus/HIV infection as well as novel molecules that regulate, or respond to, Pattern Recognition Receptor (PRR) signaling. In order to elucidate the repertoire of host proteins required for viral infection, and understand the molecular strategies adapted by these viruses as countermeasures to innate immune response, his lab uses a series of systems-level approaches, including genome-wide RNAi, proteomics and protein-protein interaction (PPI) analysis, and high content imaging. This approach is helping them to build a comprehensive cellular 'roadmap' exploited by these viruses to enable their propagation within a cell.
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Sequencing and Analysis of the Hydra Genome
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GWAS Identifies Risk Loci for Ulcerative Colitis
Abrecht, Wittig et al., Nature Genetics
Researchers present results from a genome-wide association study which identified risk loci at 7q22 and 22q13 for ulcerative colitis. Their analyses included 1,897,764 SNPs from 1,043 UC cases and 1,703 controls from Germany, and six replication panels from different regions in Europe.
People on the Move

Wellcome Trust Sanger Institute Professor Leena Peltonen-Palotie died this week of cancer at her home in Finland, according to the Sanger Institute. Peltonen-Palotie was head of human genetics at Wellcome Trust, and she held appointments at the Broad Institute at MIT and Harvard and the Institute for Molecular Medicine Finland.

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Adrian Dillon will resign from his job as executive VP of finance and administration and CFO of Agilent Technologies to become chief financial and administrative officer at Skype. He will be replaced at the beginning of April by Didier Hirsch, who currently is VP of corporate controllership and taxes and who will serve as acting CFO.
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Science
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HHS expects that in 2010 NIH will spend another roughly $5.2 billion overall in stimulus funds that were left over from ARRA's first year. NIH still has more than $1.6 billion to spend in stimulus funds for lab construction and renovation, buildings and facilities, and shared instruments.
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Correlagen Purchases Helicos Instrument to Develop New Genetic Tests

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