Sequencing and Analysis of the Hydra Genome
Chapman, Kirkness et al., Nature
An international research collaboration reports their sequencing and analysis of the Hydra magnipapillata genome, and compare it to the genomes of several other organisms. "The Hydra genome has been shaped by bursts of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of gene structure and gene content that parallel simplification of the Hydra life cycle," the authors write. They team suggests that comparisons of the Hydra genome to the reported sequences of other animals have helped them to elucidate the evolution of several of the organism's characteristics.
Cold Spring Harbor Lab to Test Multiplexed Sequencing Method in Genetic Disease Project
Though the group is not the only one that has developed a pooling method for multiplexed second-gen sequencing, it may be the first to explore its potential for clinical applications, by identifying carriers of genetic diseases in certain orthodox Jewish communities.
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