PTB Proteins Induce RNA Looping
Lamichhane, Daubner et al., PNAS
Researchers in the US and Switzerland report that polypyrimidine tract-binding proteins induce RNA looping ― a finding they deduced using FRET, NMR spectroscopy, and in vivo splicing data. They show that two PTB RNA recognition motifs can bind two distant pyrimidine tracts, bringing their 5' and 3' ends in close proximity, thus inducing loop formation.
ABI Says SOLiD 3 Run Yielded 50 Gb Human Sequence Data As Part of Disease Study with Baylor's HGSC
May 05, 2009
The SOLiD system used in the project was equipped with new bead-finding and quantitation genomic analysis software, ABI said.
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