Genome-Wide Meta-Analysis for Serum Calcium Identifies Significantly Associated SNPs near the Calcium-Sensing Receptor (CASR) Gene
Kapur et al., PLoS Genetics
An international team of researchers reports its genome-wide association study of serum calcium's association with SNPs in or near the calcium-sensing receptor gene on 3q13. "This genome-wide meta-analysis shows that common CASR variants modulate serum calcium levels in the adult general population," the researchers write, adding that their "results show that CASR is a key player in genetic regulation of serum calcium in the adult general population."
Rosetta Puts Blood-Based Cancer Screen on Back Burner to Refocus on miRNA Diagnostics
The news wasn't a complete surprise given the general difficulties in measuring and interpreting blood-borne miRNA signatures, as well as the firm's own admission in September that "technical obstacles" had been stymieing its efforts to develop the screen.
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