Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Rosetta Genomics Aims to Launch Blood-Based miRNA Colon Cancer Test in 2010
According to recently released data, the test, dubbed miRscreen Colon, can use two miRNAs to identify the disease with 91 percent sensitivity and 72 percent specificity.
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