Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Report: More Life-Science Jobs Despite Recession; Fewer Patents in Top-10 States
A report issued by Battelle Memorial Foundation and the Biotechnology Industry Organization has found that job creation by US life sciences employers survived the first year of the recession in 2008, and thrived over most of the previous two years. However, the report also showed a decline in bioscience-related patents among the top 10 states in that category.
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