Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
QB3 Opens New Incubator at UC Berkeley
The California Institute for Quantitative Biosciences hopes the Berkeley facility will enjoy the success of its QB3 Garage@UCSF incubator, which has nurtured some 28 biotech startups in two sites since opening in 2006.
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