Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Moved into Permanent Home, SRI's CADRE Boosts Proteomics Work into Rx, Dx for Infectious Diseases
CADRE's new facility gives it more than 11 times the amount of space it previously had. As a result, it will now be able to hire additional scientists and support personnel, as well as add new instrument platforms for its proteomics work.
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