Montreal Team IDs RSK Protein as the Root of Ras/MAPK Chemoresistance in Melanoma | GenomeWeb

Following results of a phosphoproteomic screen, University of Montreal researchers have tracked down a protein kinase, ribosomal S6 kinase, or RSK, that plays a central role in melanoma's resistance to chemotherapy through the Ras/MAPK pathway. According to the group, the results suggest RSK could be a promising therapeutic target in the disease.

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