Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Agilent's Proteomics Tools Segment Grows 22 Percent in Fiscal Q1; New LC, MS Tools Shine
The Bio-Analytical division saw revenues grow to $455 million, up 22 percent from $373 million a year ago. Both revenues and the revenue-growth rate were new records, company officials said. The company said the division’s profit for the quarter, $88 million, up 69 percent year-over-year, was also a new record.
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