Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
$6.8M Investment Pushes Pronota Closer To Development of Diagnostics Pipeline
The Belgian firm will use the funds, secured in the first close of its Series B financing, for the further development of diagnostic programs underway for acute heart failure, sepsis, preeclampsia, and ovarian cancer.
New to GenomeWeb? Register quickly here.