Researchers Make Progress Toward Single-Cell Sequencing, Though Key Hurdles Remain
April 12, 2011
Researchers Make Progress Toward Single-Cell Sequencing, Though Key Hurdles Remain
There are two main problems when it comes to sequencing single cells: Whole-genome amplification protocols do not amplify the genome in an unbiased manner, and PCR steps in library preparation introduce additional biases and errors.
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