NCI-Led Study Demonstrates Reproducibility of SID-MRM-MS for Protein Biomarker Verification

Individual labs have shown that multiple reaction monitoring coupled with isotope dilution mass spectrometry, or SID-MRM-MS, can be used to quantify candidate protein biomarkers in plasma, but until now no one had proven the interlaboratory reproducibility of the method or the transferability of the assays across different labs.