Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Idaho Tech Gets FDA OK for Respiratory Dx; Expects Approval for Improved Panel Soon
April 28, 2011
The FDA recently awarded 510(k) clearance to Idaho Technology's FilmArray Respiratory Panel, but the company has chosen not to commercialize the product, instead awaiting FDA clearance for a follow-on version containing two additional targets.
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